PET

Nuclear & X-ray · reads

PET is molecular imaging that uses radioactive tracers. It detects pairs of 511 keV photons produced when positrons and electrons annihilate, mapping where the tracer is concentrated. Depending on the tracer, that concentration indirectly indicates regional glucose use, cerebral blood flow, or the distribution, concentration and drug occupancy of receptor-system proteins in the brain.

Spatial resolution

1.64 mm (point spread)

Temporal resolution

100 ms (sample interval)

Field of view

1.23 L (acquired volume)

Reads

radiotracer concentration; glucose metabolism; cerebral blood flow; receptor binding/occupancy

Destructive?

non-destructive

Prerequisites

other: Fast for 4–6 hours.; other: Check blood glucose.; other: Place an IV cannula at least 10 minutes before tracer injection.; other: The patient must lie still.; other: For quantitative dynamic studies, perform arterial blood sampling.

Theoretical spatial resolution

600 µm (point spread)

Theoretical field of view

1.23 L (reachable envelope)

Description

PET is molecular imaging with radioactive tracers; its signal is pairs of 511 keV photons from positron–electron annihilation. In the brain, it measures regional glucose utilization, cerebral blood flow, and receptor-system protein distribution, concentration, and drug occupancy.

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