Open microsurgical resection

Implanted & surgical write · writes

Open surgical resection is brain surgery that cuts into, removes or disconnects brain tissue, for example taking out a tumour or parts of the temporal lobe; one variant, hemispherotomy, disconnects tissue without fully removing it. It reads nothing: the resection itself records no quantity from the brain, direct or indirect, though separate techniques such as recording from the brain surface or electrical mapping may accompany it. What it writes is the physical removal or disconnection of brain tissue, which carries greater risk of harm and is harder to repeat than less invasive energy-based ablation.

Temporal resolution
n/a
Field of view
617 cm³ (treated volume)
Reads
n/a
Writes
incised brain tissue; sacrificed brain tissue; resected/removed brain tissue; disconnected brain tissue
Destructive?
destructive
Prerequisites
surgery: Craniotomy for open resection
Theoretical spatial resolution
150–200 µm (suprathreshold extent)
Theoretical temporal resolution
n/a
Theoretical field of view
617 cm³ (reachable envelope)

Description

Open brain resection incises and removes (resects) brain tissue; related open procedures may sacrifice or disconnect tissue, e.g., hemispherotomy disconnects without complete removal. Anatomical variants include lesion/glioma resection, partial anterior temporal lobectomy with amygdalectomy, standard ATL (removing temporal neocortex, amygdala, hippocampus and parahippocampal gyrus), and selective amygdalohippocampectomy, which spares lateral neocortex. Adjuncts include awake craniotomy for direct stimulation and real-time functional mapping, neuronavigation, and sometimes intraoperative MRI or electrocorticography (ECoG); awake feasibility varies and ECoG benefit is disputed. Open resection can maximize lesion removal but carries greater morbidity and limited repeatability.

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